Servers and from email

If I want to send a campaign through multiple servers, will the from email be the default email I setup on the server or the one I specify in the campaign settings?

It would be bad if lets say 2 servers sent a campaign but only one had the correct domain matched up to where it was sending it from .

The "From" header is kept as the one from the campaign if possible, some servers will not allow this, same goes for amazon usage for example. Another exception would be if you force the FROM from the delivery server settings.
But usually it will always be the FROM from campaign.