Block ip

I find in some lists emails with different domains but on the same ip and are not real emails like for example ""
Then I want to block this ip instead of blocking email addresses so that my clients can not send to all the emails configured on that ip
By mistake I have in my contact list invalid emails but after sending the campaign I discover that despite they are invalid I discover on the interface of statistics that they opened the email and clicked Links, so I discover that they are all having ips from the USA
According to you what is this phenomenon
ip block.png / /

Try clicking on these domains please
web may be very different from email

that tool is also not telling all